
Finasteride vs Minoxidil: What the Labels and Trials Say, and Cost
Finasteride and minoxidil work differently and carry different warnings. What the FDA labels and published trials say, and what each costs online, sourced.
By Julian Caraulani · Last updated
Comparison
This guide sets out what the FDA labels and the published research say about each, what each costs at online programs, and what to ask your prescriber. We do not give doses; your prescriber picks the product and the amount.
The short answer
| Finasteride (oral) | Minoxidil (topical) | Minoxidil (oral) | |
|---|---|---|---|
| FDA status for hair loss | Approved for men | Approved, over the counter | Not approved for hair loss (off-label) |
| How it works | Blocks conversion of testosterone to DHT, the hormone that shrinks follicles | Widens blood vessels; exact hair mechanism not fully known | Same drug, taken as a tablet |
| Prescription needed | Yes | No | Yes |
| Label warnings to know | Sexual side effects, mood changes | Scalp irritation | Boxed warning for heart effects at blood pressure doses |
| Cheapest online program price | $14 a month | $8.92 a month | $18 a month |
| Cash price with your own prescription | $0.19 a tablet | Sold over the counter | $0.20 a tablet |
Prices are live from our price table, checked October 31, 2026. Every plan and its source is on our hair loss price page.
What the evidence says
Network meta-analysis, 2022. Researchers pooled 23 trials of finasteride, dutasteride and minoxidil in men. Their findings differed by end point and time point: one drug led on total hair count at 24 weeks, another on terminal hair count, and oral finasteride did well on terminal hair at 48 weeks against topical minoxidil. The authors were careful about how far this goes: "As efficacy data from head-to-head trials accumulate, there could be a better sense of the relative efficacy" (Gupta et al., JAMA Dermatology, PubMed).
Oral versus topical minoxidil, 2024. A randomized, double-blind trial in Brazil compared oral minoxidil with topical minoxidil in men for 24 weeks. Oral minoxidil "did not demonstrate superiority over topical minoxidil" on the main measure, though photos favoured it on the crown. Excess body hair was common: "The most common adverse effects in the oral minoxidil group were hypertrichosis" (Penha et al., JAMA Dermatology, PubMed).
What this means in practice: neither drug is a clear winner in the trials we cite, they work by different routes, and combining them is common. Whether a combination suits you is a decision for your prescriber.
- FDA-approved and compounded
- No FDA warning letter found
- No state list published
What the labels warn about
Finasteride. The Propecia label says it "is indicated for the treatment of male pattern hair loss (androgenetic alopecia) in MEN ONLY" and that "PROPECIA is not indicated for use in women." Reports after approval include "sexual dysfunction that continued after discontinuation of treatment" and "depression, suicidal ideation and behavior" (DailyMed: Propecia label). These are the reasons many men research "post-finasteride syndrome"; read the full label section with your prescriber.
Oral minoxidil. The tablet's label was written for severe high blood pressure, and its boxed warning says: "Minoxidil tablets contain the powerful antihypertensive agent, minoxidil, which may produce serious adverse effects." It goes on: "It can cause pericardial effusion, occasionally progressing to tamponade" (DailyMed: minoxidil tablets label). Hair loss prescribing uses much lower amounts than the label's blood pressure use, but the label is the only FDA-reviewed safety document for the tablet, so ask how your prescriber will monitor you.
Topical finasteride. Sprays and solutions that add finasteride to minoxidil are compounded. The FDA says: "Currently, there is no FDA-approved topical formulation of finasteride." (FDA alert on compounded topical finasteride)
What each costs online
| Product | Lowest all-in program price | Where |
|---|---|---|
| Oral finasteride | $14 a month | Keeps; also Ro at $16 |
| Oral minoxidil (off-label) | $18 a month | Happy Head, 6-month supply; also Strut Health at $18.33 |
| Topical minoxidil (over the counter) | $8.92 a month | Keeps; also sold in any pharmacy |
| Topical finasteride and minoxidil (compounded) | $35 a month | Hims; see the FDA alert above |
The cheapest monthly figures usually need a 3- to 12-month plan. Each review lists the month-to-month price and the cancellation terms. Program prices for plain finasteride are side by side on our finasteride price page, and for oral minoxidil on our oral minoxidil price page.
Questions to ask before you pick
- Is the product FDA-approved for this use? Oral finasteride and topical minoxidil are; oral minoxidil and every topical finasteride are not.
- How will side effects be followed up? A program should tell you how to reach the clinician after the first prescription.
- What happens if I stop? Hair gained on either drug tends to be lost after stopping, so think in years, and price the plan you can keep paying.
- Can the prescription go to my own pharmacy? Cash prices for both generics are a fraction of most program prices.
Thinking of using both? Finasteride and minoxidil together prices the combination products against two separate generics, and our best hair loss treatment online ranks the programs.
Questions
FAQ
Is finasteride or minoxidil better for hair loss?
The trials we cite do not name a single winner: results differ by measure and timing, and the drugs work differently. Many prescribers use both. Ask yours which fits your pattern of hair loss.
Can I use finasteride and minoxidil together?
Many men do, and several programs sell both, separately or as compounded combinations. Combinations in one spray or chew are compounded and not FDA-approved.
Is oral minoxidil FDA-approved for hair loss?
No. It is approved as a blood pressure tablet and prescribed off-label for hair loss. Its label carries a boxed warning about heart effects.
How much does finasteride cost compared with minoxidil?
Online, finasteride starts at $14 a month and oral minoxidil at $18. With your own prescription, both generics cost well under a dollar a tablet at Cost Plus Drugs.
Does finasteride cause permanent side effects?
The Propecia label lists sexual dysfunction that continued after stopping treatment among reports received after approval. How often that happens is debated; discuss it with your prescriber before starting.
Which is cheapest: pills or a spray?
Plain tablets. Compounded sprays and chews usually cost two to three times the tablet at the same program; see the [best programs](/best) and every price on our [hair loss price page](/cost/hair-loss).